Having opened the scoring after simply six minutes by way of a penalty from Ayew, CAR ended the primary half within the lead after Louis Mafouta netted a brace to overturn the end result.
However, the Black Stars got here again stronger within the second half, with two extra objectives from Ayew and one other strike from Abdul Fatawu Issahaku propelling the hosts to a 4-3 win on the Baba Yara Sports Stadium regardless of Mafouta finishing his hat-trick too.
Ghana coach Otto made three modifications to the facet that beat Mali final week, with Jordan Ayew, Abdul Fatawu Issahaku and Kamaldeen Sulemana approaching for Antoine Semenyo, Ernest Nuamah and Tariq Lamptey.
Addo additionally reverted to a again 4, with Alidu Seidu, Gideon Mensah, Alexander Djiku and Mohammed Salisu defending Lawrence Ati-Zigi within the submit.
Thomas Partey as soon as once more partnered with Abdul Salis Samed in midfield, with Sulemana and Issahaku working from the flanks.
Mohammed Kudus was additionally maintained from the group that beat Mali 2-1 4 days in the past in Bamako, whereas Ayew led the assault after coming off the bench to attain in opposition to the Eagles.
The Baba Yara Stadium was despatched right into a frenzy simply two minutes into the sport when a surging run by Issahaku led to a penalty after he was introduced down within the CAR field.
Ayew stepped as much as calmly convert, making it his fifth aim in his final 4 matches for his nation, because the Black Stars took the lead.
While Ghana seemed to construct on their early lead, their dominance was truncated by a aim in opposition to the run of play after Mafouta outran each Salisu and Djiku to web the equaliser within the eleventh minute.
Six minutes later, a poor again move by Djiku practically resulted in one other aim for CAR, however Ati Zigi reacted quickest to thwart Karl Namnganda’s effort.
Sulemana was additionally offered with an excellent alternative following a blistering counter-attacking transfer however the Southampton winger made a poor determination by taking pictures off track regardless of having higher choices to his left and proper.
With the primary half heading for a stalemate, Mafouta surprised Ghana together with his second of the evening after making the most of Mensah’s decisiveness to attain.
The second half of the sport was, nevertheless, a unique proposition, as Ghana upped the ante and started to make use of the flanks extra, as Sulemana and Issahaku swapped positions.
After a sequence of close to misses by Sulemana and Mensah, the latter delivered a pin-point cross which was met with a towering header by Ayew on the far submit to make it 2-2.
Two minutes later, Issahaku put Ghana forward after his deflected effort discovered its strategy to the again of the web earlier than Ayew accomplished his hat-trick following a goalmouth scramble within the 69thminute.
There was, nevertheless, nonetheless time for some late drama, with Mafouta scoring his third aim of the evening by way of a spectacular free-kick to make it 4-3.
Meanwhile, the Black Stars have now moved to the highest of Group I within the CAF World Cup qualifiers, three factors forward of each Comoros and Madagascar, who will face Chad and Madagascar, respectively, on Tuesday.